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대학원 세미나

11/21(목)16시 연사:김희남 (고려대학교 바이오시스템의과학과 교수)
작성자 관리자조회수 45날짜 2019.11.20
일시: 11월 21일(목) 4:00PM

장소 : 벤처관 711호

강사: 김희남 (고려대학교 바이오시스템의과학과 교수)

제목: Human gut microbiota and modern diseases

내용: The gut microbiota plays a pivotal role in human physiology and development, and their malfunction has been linked to various chronic diseases. Increased incidences of these “modern diseases” in a few decades are thought to be largely due to the negative effect of the modern civilization through excessive hygiene practices and diet lacking plant fiber. In my laboratory, we are investigating the interrelationship between the aberrant gut microbiota function and modern diseases. We recently discovered that a specific subspecies-level dysbiosis in Faecalibacterium prausnitzii underlies the onset and/or progression of atopic dermatitis. On the other hand, exposure to antibiotics also can cause damage to the gut microbiota. Although it is well established that such damage is initiated by the disruption of gut microbiota homeostasis, the long-lasting effects of such damage are poorly understood. One possible cause for such long-lasting damage is a large-scale induction of the stringent response in the gut microbiota triggered by antibiotic exposure. This induction can result in the rise of antibiotic-tolerant populations that persist for a long time, causing recalcitrant structural alterations. While current understanding of the gut microbiota physiology is in its infancy, it will be of tremendous significance in the future.
이전 11/28(목)16시 연사:배진규 (㈜셀트리온 팀장)
다음 11/14(목)16시 연사:조윤성 (㈜클리노믹스 게놈연구소 연구소장)